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Chromatography Filtration Solutions for HPLC, UHPLC & LC-MS

High-performance syringe filters and membrane disc filters engineered for reliable, reproducible chromatography results.

  • Ultra-clean filtration — minimal extractables
  • Stable chromatographic baselines guaranteed
  • Protects expensive HPLC columns from particulates
  • Compatible with HPLC, UHPLC & LC-MS systems
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Trusted by Analytical Laboratories Worldwide

ISO 9001:2015Quality Certified
GMP CompliantPharma Grade
Global Supply30+ countries
GLP CompatibleLab Standards
REACH TestedLow Extractables
Fast DispatchPan-India Delivery
500+
Laboratories Served
Across India & globally
0.2µm
Precise Pore Control
UHPLC & LC-MS grade
100%
Particle Retention
Validated per batch
15+
Membrane Types
PVDF, PTFE, Nylon, MCE & more
The Challenge

Why Filtration Is Critical in Chromatography

Unfiltered or poorly filtered samples cause costly system failures and unreliable analytical data. Here's what's at stake:

  • Column Blockage & Reduced Lifespan

    Particulate matter clogs packed HPLC columns, causing irreversible pressure build-up and expensive column replacement.

  • Baseline Noise & Ghost Peaks

    Matrix interferences introduce noise and false peaks, invalidating quantitative analysis and requiring repeat runs.

  • Pressure Instability & System Errors

    Inconsistent back-pressure from particle contamination triggers system shutdowns and aborts analytical runs.

  • Pump & Detector Damage

    Abrasive particles wear pump pistons, seals, and check valves — leading to costly repairs and instrument downtime.

Sample-to-Injection Flow: What Can Go Wrong

Unfiltered Sample Particles, proteins, matrix compounds
HPLC Injection ❌ Injected without filtration — high risk
Column Blockage Pressure spike → column failure
✓ The Filtrationhub Solution
Syringe Filter (0.22µm) Removes all particles before injection
Clean Chromatogram Stable baseline · Accurate results
Our Products

Chromatography Filtration Products

Precision-engineered filtration solutions designed specifically for demanding chromatography workflows.

Syringe Filters

Syringe Filters

Ultra-low extractable syringe filters for HPLC, UHPLC, and LC-MS sample preparation. Available in PVDF, Nylon, PTFE, MCE and Cellulose Acetate membranes.

  • Ultra-low extractables — minimal interference
  • Precise pore structure (0.20µm, 0.22µm, 0.45µm)
  • Clog-resistant with glass fiber pre-filter
  • High chemical compatibility with solvents
  • Available in 4mm, 13mm, 25mm, 33mm diameters
Pore Size
0.20–0.45µm
Diameter
4–33mm
Membrane
PVDF, PTFE, Nylon
Pack Size
100/pk, 500/pk
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Membrane Disc Filters ↓ Sample In ↓ Filtered Out

Membrane Disc Filters

High-throughput membrane disc filters for mobile phase filtration and sample clarification. Ideal for vacuum filtration systems used in HPLC mobile phase prep.

  • High flow rate — low differential pressure
  • Low pressure drop for rapid throughput
  • Compatible with vacuum filtration systems
  • Broad chemical resistance (aqueous & organic)
  • Available 25mm, 47mm, 50mm, 90mm, 142mm
Pore Size
0.1–10µm
Diameter
25–142mm
Membrane
MCE, PVDF, Nylon
Pack Size
25/pk, 50/pk
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Industries & Applications

Who Uses Filtrationhub Filtration Products?

From pharmaceutical QC to academic research — our filters are validated for demanding analytical environments across sectors.

Pharmaceutical QC Labs

API testing, finished product analysis, dissolution media filtration, and stability studies demand the highest-purity filtration. Filtrationhub's low-extractable membranes are compliant with ICH and USP guidelines.

HPLC Assay Dissolution ICH Compliant

Bioanalytical & CRO Labs

LC-MS/MS quantitation of drugs in plasma, urine, and tissue requires ultra-low background. PVDF and PTFE filters with documented extractable profiles protect your mass spec signal integrity.

LC-MS/MS Plasma Matrix PK Studies

University & Research Labs

Academic researchers need reliable, cost-effective filtration for natural product analysis, metabolomics, proteomics, and environmental chemistry. Bulk pricing and COA documentation available.

Metabolomics Proteomics Environmental

Food & Beverage Testing

Pesticide residue analysis, mycotoxin detection, and adulteration testing in complex food matrices require clog-resistant filters with broad chemical compatibility and high particle loads.

Pesticide Mycotoxin FSSAI

Environmental & Water Testing

Ground water, effluent, and drinking water analysis demands high-throughput membrane disc filters. Filtrationhub's vacuum filtration discs handle high-turbidity samples with minimal clogging.

Water Analysis Effluent NABL

Clinical & Diagnostic Labs

Therapeutic drug monitoring and clinical biomarker analysis using HPLC-UV and LC-MS requires consistent, sterile-grade filtration with documented biocompatibility for biological matrices.

TDM Biomarkers Serum
Filtration Workflow

Recommended Chromatography Filtration Workflow

Follow this validated workflow for consistent, reliable HPLC and LC-MS results every time.

Sample Preparation

Dissolve & dilute in appropriate solvent

Pre-Filtration

Remove large particles with pre-filter (5µm)

Syringe Filtration

0.22µm syringe filter before injection

Mobile Phase Filtration

Membrane disc filter for solvent prep

Degassing

Sonicate or use online degasser

HPLC Injection

Clean sample → reliable chromatogram

Why Filtrationhub

Why Choose Filtrationhub Filtration?

Built for analytical laboratories that demand precision, reliability, and consistent performance run after run.

Advanced Membrane Technology

Proprietary casting processes deliver membranes with tight pore size distribution for precise, reproducible filtration at analytical scale.

Global Manufacturing Standards

Manufactured in ISO-certified facilities with stringent QC protocols — every batch tested before dispatch to your laboratory.

High Chemical Compatibility

Extensive membrane material range — PVDF, Nylon, PTFE, MCE, PES — compatible with aqueous buffers, organic solvents, and aggressive acids/bases.

Consistent Quality Control

100% bubble-point tested membranes with documented lot-to-lot consistency. Certificate of Analysis available for every batch.

Designed for Chromatography Labs

Every design decision optimized for HPLC workflows — from housing geometry that minimizes dead volume to membranes that produce the lowest extractable profiles.

Trusted by Research Institutions

Used in pharmaceutical QC labs, universities, contract research organizations, and government analytical laboratories across India and beyond.

Membrane Selection Guide

Which Membrane is Right for Your Application?

Use this quick reference table to select the correct membrane material for your HPLC, UHPLC, or LC-MS workflow.

Membrane Best For Aqueous Organic Solvents Strong Acids/Bases LC-MS Grade Protein Binding Recommended For
PVDF Most Popular HPLC, LC-MS, Protein samples ✓ ✓ Partial LC-MS Grade Low Pharmaceutical QC, Bioanalytical
Nylon (PA) Aqueous buffers, mild organic ✓ ✓ ✗ Standard Moderate Mobile phase prep, General HPLC
PTFE Solvent Resistant Aggressive solvents, strong acids With wetting ✓ ✓ LC-MS Grade Very Low Strong acid/base matrices, Non-aqueous HPLC
MCE (Mixed Cellulose) Aqueous samples, low protein binding ✓ ✗ ✗ Standard Very Low Water testing, Aqueous buffers
PES (Polyethersulfone) Biological fluids, cell culture ✓ Limited ✗ Standard Very Low Proteins, Enzymes, Biologics
Cellulose Acetate (CA) Aqueous, low-protein binding needed ✓ Limited ✗ Standard Low Clinical samples, Diagnostics
Not sure which membrane is right for your application? Contact our technical team — we'll recommend the exact membrane type, pore size, and filter diameter for your specific matrix and instrument. Request a free consultation →
Getting Started

How to Get Your Free Product Samples

We make it easy to evaluate Filtrationhub filtration products in your own laboratory before committing to a bulk order. Here's exactly what to expect:

1

Submit Your Sample Request

Fill in the short form on this page with your name, lab details, product interest, and application. Takes less than 2 minutes.

Takes ~2 minutes
2

Technical Review & Sample Pack Selection

Our technical team reviews your application and selects the ideal membrane type, pore size, and filter format for your specific workflow.

Within 24 business hours
3

Sample Dispatch — Pan-India Delivery

Your sample pack is dispatched from our Ahmedabad warehouse with a Certificate of Analysis and product data sheet included.

2–5 business days delivery
4

Evaluate in Your Lab & Place Order

Test in your real workflow. Our team follows up to answer any questions, share application notes, and process your bulk order when you're ready.

No obligation to order

What's Included in Your Sample Pack

Every sample request is fulfilled with a curated selection based on your application.

10–25 Syringe Filters Recommended membrane type & pore size for your matrix
5–10 Membrane Disc Filters For mobile phase or large-volume sample filtration
Certificate of Analysis (COA) Lot-specific quality documentation for each product
Application Data Sheet Chemical compatibility chart, extractable profile & test data
Technical Support Access Direct line to our analytical chemist team for evaluation guidance
100% free — no payment required for samples
No obligation to place a bulk order
Available to all registered analytical laboratories
Pan-India shipping — Ahmedabad warehouse dispatch
Request Your Free Sample Pack →
Testimonials

What Analytical Scientists Say

★★★★★
"

Reliable filtration performance across our entire HPLC workflow. The PVDF syringe filters show extremely low extractables even with complex pharmaceutical matrices — we've had zero ghost peak issues since switching to Filtrationhub.

AR
Dr. Anjali Rathore Senior Analytical Scientist, Pharma QC Lab · Ahmedabad
★★★★★
"

We tested three brands of membrane disc filters for our LC-MS mobile phase prep. Filtrationhub's 0.22µm PVDF discs consistently delivered the cleanest baselines and highest flow rates. The sample-to-sample reproducibility is outstanding.

VM
Vikram Menon Lab Manager, Contract Research Organization · Bangalore
★★★★★
"

Column lifetime has increased significantly since we standardized on Filtrationhub syringe filters. The technical team was helpful in recommending the right membrane for our acetonitrile-heavy gradient system. Fast delivery and good stock availability.

PS
Dr. Priya Sharma Head of R&D, API Manufacturer · Hyderabad
★★★★★
"

Our university research lab runs 50–80 HPLC injections daily. Filtrationhub Nylon filters are cost-effective and perform consistently for aqueous buffer systems. Technical documentation is clear and the Certificate of Analysis is always provided.

RK
Prof. Rajesh Kumar Department of Chemistry, Central University · Delhi
Quality Assurance

Certifications & Standards

ISO 9001:2015

International quality management system certification

GMP Compliant

Good Manufacturing Practice for pharmaceutical-grade production

GLP Compatible

Good Laboratory Practice — suitable for regulated analytical environments

REACH Compliant

European Union chemical safety and registration standard

FAQ

Frequently Asked Questions

Everything you need to know about our filtration products for chromatography applications.

What pore size filter is used for HPLC sample preparation?
For standard HPLC applications, a 0.45µm syringe filter is commonly used for sample preparation. For UHPLC systems with sub-2µm particles and for LC-MS applications, a 0.22µm filter is recommended to protect the column and avoid back pressure issues. Filtrationhub offers both pore sizes across multiple membrane types.
Why is filtration important in chromatography?
Filtration is critical because particulate matter in samples or mobile phases can block the HPLC column, causing irreversible pressure build-up and premature column failure. Particles also cause baseline noise, ghost peaks, and can physically damage pump pistons and check valves. Proper filtration protects expensive instrumentation and ensures data reliability.
Which membrane material is best for LC-MS applications?
For LC-MS applications, PVDF (Polyvinylidene Fluoride) and PTFE membranes are typically preferred due to their ultra-low extractable profiles — critical to avoid ion suppression and interference in mass spectrometry. Filtrationhub's LC-MS grade PVDF syringe filters are specifically tested for low background signal and are widely used in pharmaceutical and bioanalytical labs.
How do I choose between syringe filters and membrane disc filters?
Syringe filters are used for individual sample preparation before injection — typically for volumes up to 100mL. Membrane disc filters (used with vacuum filtration apparatus) are designed for larger volume filtration such as mobile phase preparation (500mL–5L volumes). For a complete chromatography workflow, both are typically used together: disc filters for mobile phase and syringe filters for samples.
Can I request product samples before placing a bulk order?
Absolutely. We encourage laboratories to evaluate our products in their specific workflows before committing to a bulk purchase. Fill out the sample request form on this page — our technical team will review your application and dispatch appropriate samples within 2–3 business days. We also provide technical support to help you select the right membrane type and pore size for your application.
Do you supply across India? What are typical lead times?
Yes, we supply pan-India via our distribution network. Standard stock items typically ship within 1–2 business days from our Ahmedabad warehouse. Delivery to major metro cities (Mumbai, Delhi, Bangalore, Hyderabad, Chennai) is usually 2–4 business days. For institutional and bulk orders, we offer scheduled delivery and consignment stock arrangements.
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Improve Chromatography Results with Reliable Filtration

Join 500+ laboratories across India using Filtrationhub filtration solutions for HPLC, UHPLC, and LC-MS workflows.

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